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For the development of Arthro-5, exercise physiologist Kris Kuiper reviewed various well-known and lesser-known ingredients. In consultation with scientist colleagues and based on their collective findings, 6 ingredients which complement each other particularly well were finally selected.
The combination of these ingredients and the use of the proper, high dosages make Arthro-5 a unique product and the ultimate dietary supplement for joint cartilage protection worldwide! It offers the highest chance of benefit and is therefore very popular among our customers.
Arthro-5 contains the well-known ingredients glucosamine, chondroitin, MSM, and vitamin C as well as the lesser-known but no less important ASU and hyaluronic acid. Some of these substances are produced naturally in the human body. They are important building blocks for cartilage, joint capsule, tendons, and other connective tissue. It is possible to replenish these substances by means of supplements. In Arthro-5 they are combined in one product which is hence the most complete and potent supplement for healthy joints.
Read more about the composition below.
1. Glucosamine sulphate
1500 mg per daily dose
Most utilised joint protection substance in the world - and for good reason. Glucosamine helps in maintaining cartilage, joint casings, tendons and other connective tissues. It also contributes to the maintenance of joint fluid, thus supporting joint lubrication. And Arthro-5 contains the proper, high dosage of 1500 mg of glucosamine per day.
2. Chondroitin sulphate
1200 mg per daily dose
Valuable ingredient that reinforces glucosamine. Even more important is the fact that chondroitin protects the cartilage by keeping a few key enzymes in balance. Glucosamine and chondroitin thereby complement each other excellently. Scientific research now shows that taking both supplements at the same time significantly enhances results.
3. ASU
300 mg per daily dose
Specially processed extract of avocado and soy oil. Despite extremely persuasive scientific evidence, ASU is still a relatively unknown supplement in most countries after glucosamine and chondroitin. Among other benefits, it can promote the creation of collagen, which contributes to cartilage strength.
4. MSM
1500 mg per daily dose
Popular with the public for years, but repudiated for many years by the scientific community. In the meantime scientific support for the use of MSM has grown: it has a beneficial influence on joints. Adding it to glucosamine leads to faster and better results.
5. Hyaluronic acid
80 mg per daily dose
A relatively new nutritional supplement. Hyaluronic acid is the most important component of the lubricating fluid in the joints. It also enables our joints to absorb shocks. For this reason, doctors have been giving injections with hyaluronic acid directly into the joints for almost 20 years. It has now also been established that it has a beneficial physiological influence as a nutritional supplement as well. It is important to note that only hyaluronic acid with a high molecular weight is useful. A lot of (cheap) hydrolised hyaluronic acid is available. Its molecular weight is much lower, with the result that its effect is counterproductive.
6. Vitamin C
18 mg per daily dosage
Vitamin C contributes to normal collagen formation and hence to normal cartilage function.
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Glucosamine.com has been licensed to use the patented combination of chondroitin and ASU (EP2101799).
Ask Kris Kuiper, MSc,
exercise physiologist
The ingredients in Arthro-5 need time to build up to an effective level in the body. The time it takes before you notice any improvement varies from person to person and from joint to joint.
For many users, the positive effect is already noticeable after one or two weeks. For others, it takes one, two or three months and for some, even six months or more. We recommend trying Arthro-5 for at least three months (three bottles) before making a final decision and to certainly not give up too soon if you do not notice any effects for a few weeks. It would be a shame to miss out on improvements.
The effect is often noticed quickest in the knees and hips (after a few weeks). This is followed by the shoulders, hands and feet (after a few months). The back and neck take the longest (6 to 12 months).
The success rate is around 80% to 90%. Read more below.
The success rate is around 80% to 90%, depending on your personal situation. Should you not notice any difference after six months, it is probably not useful to keep taking Arthro-5 (in case of back or neck pain, it is important to keep going for longer).
Most people come to the conclusion that it is worth taking longer and take Arthro-5 continuously. There is no problem with that. It can be taken safely for years.
Arthro-5 is not our cheapest product. Still, the price that you pay for this supplement is very competitive, given its many highly-dosed high-quality ingredients. With a 'normal' price structure, a product with similar ingredients - which does not exist - would cost at least €/£ 75 to €/£ 100.
Due to the many highly dosed ingredients, the recommended daily dose is 6 capsules (which may be taken in one go or staggered throughout the day). That's a lot. But we think it is important to provide proper, effective doses rather than lower amounts that are easier to take but won't do you much good.
By choosing Arthro-5 you are choosing quality. We can guarantee it in the following way:
Safe product. These Western producers fulfill GMP and HACCP requirements. This means that they follow strict procedures which ensure food safety and hygiene.
Independently tested. The end product is randomly tested for heavy metals and biological pollutants by the independent laboratory NutriControl. Click on the microscope symbol below for the most recent test results. Read more about the independent laboratory tests here.
Proper, high dosage. Many dietary supplements contain dosages that are too low and ineffective. Arthro-5 contains the proper, high dosages. This is the reason that the daily dosage is 6 capsules (which may be taken simultaneously).
Capsule form. Arthro-5 comes in capsules instead of tablets. Capsules are absorbed more quickly and have less chance of causing gastric hypersensitivity. Another advantage of capsules is that they are easier to swallow than rough capsules with hard edges. Whoever does not want to or cannot take the capsules, can easily open them and use only the powder.
Specialist since 2000. Glucosamine.com is a specialist in dietary supplements for healthy joints. The company was founded in 2000 by exercise physiologist and human movement scientist Kris Kuiper and has developed several unique supplements since then. Plenty of knowledge and experience is available about the effect and the safety of these supplements.
Arthro-5 contains ingredients that serve as nutrition for the cartilage and other tissues in and around your joints. A continuous supply of these ingredients is important to achieve optimum results.
If you pause or stop taking Arthro-5, the beneficial effects that you have achieved will largely disappear again within a few weeks or months.
We therefore advise against using Arthro-5 temporarily or for shorter amounts of time. Continuous use provides the best results by far. Arthro-5 can be safely used for years at a time.
180 capsules.
Contents per capsule (per 6 capsules):
The glucosamine is extracted from glucose from corn (not genetically modified). Chondroitin is a cartilage extract that comes from beef. ASU is extracted from soy and avocado (not genetically modified). MSM is a natural sulphur compound. hyaluronic adid is a cartilage extract from poultry.
Allergens: Soy.
Free of gluten, milk and lactose.
The recommended use is 6 capsules of Arthro-5 per day.
The capsules may be taken simultaneously or distributed throughout the day. It is preferable to take the capsules at mealtime(s) or with plenty of water.
Do not surpass the maximum recommended dosage. Dietary supplements must not be used as a substitute for a varied diet.
Do you have difficulty swallowing capsules? You can open the capsule by separating the two halves and just use the powder. You can combine it with water, fruit juice, or yoghurt, for instance.
The ingredient glucosamine in Arthro-5 can have an influence on the effect of vitamin K antagonists. These are anticoagulant coumarin-based medicines (marcoumar, coumadin, fenprocoumon, acenocoumarol, and warfarin). Do not take this supplement in combination with this type of medication without consulting a doctor. Other blood thinners do not pose a problem.
Do not take during antibiotic treatment.
Do not take if you suffer from glaucoma (increased eye pressure).
Do not take during pregnancy or the breastfeeding period.
Diabetics must check their blood sugar level during the first weeks of use.
Read more about the safe use of Arthro-5 below.
Arthro-5 can be taken safely for a long time. It does not have any serious side effects, in contrast to many painkillers. There is no problem even if it is taken for years.
Research into long-term use (2-3 years) of the ingredients in Arthro-5 has not identified any serious side effects. There are no indications that even longer use would not be safe. Many of the ingredients have been available as dietary supplements for decades. During that period, no serious side effects have ever been reported.
Some precautions must be taken in certain conditions and if taking certain medicines. You will find more information below.
Blood thinners
The ingredient glucosamine in Arthro-5 can have an influence on the effect of vitamin K antagonists. These are anticoagulant coumarin-based medicines (marcoumar, coumadin, fenprocoumon, acenocoumarol, and warfarin). Do not take this supplement in combination with this type of medication without consulting a doctor. Other blood thinners do not pose a problem.
Antibiotics
The ingredient glucosamine can have an influence on the effect of some antibiotics - it can increase or reduce the effect. We recommend not to take Arthro-5 during antibiotic treatment.
Glaucoma (increased eye pressure)
In July 2013, the results of a small study on the effect of the ingredient glucosamine on patients with glaucoma (increased eye pressure) were published. The test subjects are 6 men and 11 women with an average age of 76 years (62 to 90 years of age). The study identified that the supplement can increase eye pressure in most of these patients. Suspending its use allows the eye pressure to drop again. The average difference in eye pressure measured is 3 mm Hg.
Since this is a small study, its design does not comply with a number of important guidelines for scientific research. The scientists also indicate that the study must be confirmed with a larger, better-designed study. Nevertheless, we assume that the effect is real and therefore give the following advice:
If you have glaucoma we recommend that you do not take Arthro-5. A second possibility is to have the eye pressure measured several times once you have started taking it. Important: this precaution is only for people who already have glaucoma. There are no indications that Arthro-5 can result in increased eye pressure in healthy people.
If you are looking for an alternative, try ASU Forte or Chondroitin. These two supplements do not have an effect on glaucoma. They can be combined for an even better result.
Diabetes type 2 (adult-onset diabetes)
There are indications that blood sugar level can be affected in people with diabetes type 2 (adult-onset diabetes) during use of the ingredient glucosamine. We therefore recommend that diabetes patients regularly check their blood sugar level when they start taking Arthro-5.
Another possibility is to choose an alternative supplement. Neither ASU Forte nor Chondroitin affect people with diabetes type 2. These two supplements can be combined for an even better result.
Potassium-restricted diet
The ingredient glucosamine is stabilized with potassium chloride. A daily dosage (6 capsules) contains 268 mg of potassium. This is slightly more than the quantity of potassium in half a banana or 4 slices of wholegrain bread. An increased intake of potassium can however have adverse effects in people with seriously impaired kidney function. The intake of potassium must also be restricted if taking potassium-sparing medicines.
Gastrointestinal hypersensitivity
The ingredient glucosamine is a substance which is naturally present in the body. No serious side effects have ever been observed. The mild side effects which occur in some people usually reflect gastrointestinal hypersensitivity. Nausea and excess gastric acid are the usual effects in those cases. Constipation or, conversely, diarrhoea, occur less frequently. Nausea and excess gastric acid can in general be prevented by taking Arthro-5 during or soon after meals.
Pregnancy/breastfeeding
Do not take Arthro-5 if you are pregnant, have the intention to become pregnant, or are breastfeeding. The supplement has a very favourable safety profile but no studies have been carried out which can rule out a possible adverse effect on the (unborn) child.
Use at a young age
Use by children and teenagers (up to 18 years of age) is discouraged. As a guiding principle, the body must be 'fully grown' in order to start taking it. 'Fully grown' refers to both bone development and hormonal development. The reason that we make this recommendation is that no research has been carried out to determine whether it is safe for children and teenagers.
